Plant Transcription Factor Database
Previous version: v3.0
Ocimum tenuiflorum
ARF Family
Species TF ID Description
Ote100018721021ARF family protein
Ote100026010011ARF family protein
Ote100045940051ARF family protein
Ote100045940052ARF family protein
Ote100048140061ARF family protein
Ote100064310021ARF family protein
Ote100084880061ARF family protein
Ote100090660121ARF family protein
Ote100094190111ARF family protein
Ote100134910171ARF family protein
Ote100136040141ARF family protein
Ote100150310021ARF family protein
Ote100172530041ARF family protein
Ote100190950131ARF family protein
Ote100202020161ARF family protein
Ote100202020221ARF family protein
Ote100219760101ARF family protein
Ote100224720091ARF family protein
Ote100228140031ARF family protein
Ote238047090011ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969